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KMID : 0370219600050010056
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Yakhak Hoeji
1960 Volume.5 No. 1 p.56 ~ p.57
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Animal Tests of New 5-Chloro-8-quinolinol Derivatives as Amebicides
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Abstract
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Three new 5-chloro-8-quinolinol derivatives such as
5-chloro-7-[4-(2-N-pyrrolidylethyl)-1-piperidylmethyl]-8-quinolinol
5-chtoro-7-[4-(2-N-piperidylethyl)-1-piperidylmethyl]-8-quinolinol
and 5-chloro-7-[2-N-morpholinylethyl)-1-piperidylmethyl]-8-quinolinol
were synthesized and found to be effective against Entamoeba histolytica in vitro and against experimental intestinal amebiasis in rats.
(Received November 11. 1959)
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